They are analyzing the benefits of breast milk to provide a new bioactive ingredient

BioFoodTech start-up Exosomm investigates the natural mechanisms inherent mother’s milk people to create a new bioactive ingredient that can potentially support millions of adults with inflammatory disorders.

Based on its scientific discoveries, Exosomm has developed an innovative technology that isolates exosomesnatural particles in breast milk that play an important role in the healthy development of the immune system.

The company recycles by-products from the traditional cheese-making process to create this powerful functional ingredient for the nutraceutical category.

Although still a young company, it has already reached commercial production capacity for its patent-protected exosomes for space. medical food.

Breast milk stands out as a key vital resource for babies essential elemental nutrients necessary to promote optimal growth and well-being.

It is associated with protection against various diseases, such as infections, inflammation and obesity, and plays a key role in the development of the immune system. Scientific research attributes these benefits mainly to the presence of exosomes.

Advantages of exosomes

Exosomes are small nanoparticles produced by the body’s cells that naturally accumulate in high concentrations in breast milk. They contain microRNA beneficial: small, single-stranded, non-coding RNA molecules that studies have shown to have a significant impact on early childhood development, as well as on the future health of the baby.

The company’s research team found that different mammals (humans, cows or sheep) share a similar composition of exosomes, indicating the evolutionary importance of exosomes in offspring.

In that sense, Shimon Reif, MD, head of the Department of Pediatrics at the Hadassah Medical Center in Jerusalem published findings from their research, revealing the potential role of exosomes in reducing the burden of heart-related disorders immune system. Such as inflammatory bowel diseases (IBD, such as Crohn’s disease and colitis), diabetes and metabolic disorders in adults.

We believe that adults can benefit from exosomes as well valuable nutrient to help better control chronic metabolic inflammatory disorders and improve overall well-being. More clinical research is underway, and we are currently focusing our studies on the role of exosomes in the treatment of IBD conditions, such as Crohn’s disease and colitis,” emphasizes Reif.

Exosomes can also be integrated as a functional ingredient in numerous food and beverage applications. Photo: Freepik

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A new role for side streams of cheese

Developed at the medical center in Hadassah University from Israel, the technology consists of exosomes naturally isolated from recycled by-products of the traditional cheese production process for use as a bioactive ingredient.

This step was achieved by Dr. sc. Regina Golan-Gerstl, co-founder and technical director of EXOSOMM and full professor and director of the Pediatric Laboratory at Hadassah Medical Center. Golan-Gerstl has developed a highly effective, safe and economical isolation method bovine milk exosomes.

One of the challenges was to transform the developed technology into a commercially viable process. It was essential to find a facility that could collect leftover whey from cheese production and process it in a way that ensured the isolated exosomes retained their unique set of bioavailable properties, explains Netta Granot.

Experts point out that they used a completely natural process, without chemicals, while complying with all regulations related to food safety and quality.

Furthermore, it was important to get the benefits of milk without any burden of milk production. That’s why they launched a circular system that depends exclusively on the lateral flow of serum from cheese industry.

In conclusion, the startup’s key targets are medical food brands and nutritional formulas intended for special dietary needs. Exosomes can also be integrated as a functional ingredient in numerous food and beverage applications.

Team Exosomm
Researchers at the Department of Pediatrics at the Hadassah Medical Center in Jerusalem: Photo: Exosomm

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